Guided by microtubule dynamics, cells naturally migrate to vulnerable areas in the body. This inherent programming is the source of multiple health benefits and disadvantages. For example, in the case of an injury, such as damaged tissue or vasculature, cells must migrate to the affected area to drive regeneration. However, the injury itself triggers microtubule disassembly, which inhibits cell migration and slows or, in some cases, prevents the healing process.
Conversely, in the case of disease, alterations in microtubule dynamics help to slow progression.